姜大朋 主任医师

博士生导师兼任专业学位导师
科室：普外科
专业：儿科学

中华医学会小儿外科学分会青年委员；中国医促会泌尿健康促进分会尿道修复与重建学部委员，中华医学会男科学分会儿童男科学组青年委员。《中华生物医学工程杂志》青年编委，《中华小儿外科杂志》特约编委。

个人简介

姜大朋，男，1978-5-2，研究方向是儿童实体瘤力学微环境。2010年博士后流动站出站。曾发表研究类SCI论文30余篇。主持国家自然科学基金等课题7项；获实用新型专利7项。美国匹兹堡大学访问学者。2017年晋升为主任医师。入选2019年上海市“医苑新星”青年医学人才培养资助计划（杰出青年医学人才类）。从事小儿实体肿瘤及普外科常见病的微创腔镜手术临床研究及儿童实体瘤力学微环境调控方面的基础研究。中华医学会小儿外科学分会青年委员；中国医促会泌尿健康促进分会尿道修复与重建学部委员，中华医学会男科学分会儿童男科学组青年委员。《中华生物医学工程杂志》青年编委，《中华小儿外科杂志》特约编委。

研究方向

儿童实体瘤力学微环境

姜大朋

jdp509@163.com

招生信息

序号	专业	招生类型	招生人数	年份
1	儿科学	学术型硕士	1	2022
2	儿外科学	专业性硕士	1	2022
3	儿科学	学术型博士	1	2023
4	儿科学	学术型博士	1	2024

姜大朋

jdp509@163.com

科研项目

1. 国家自然科学基金，81972139，BMSCs源exosome通过MFG-E8/ɑvβ3integrin调控老龄肌腱干细胞生物学特性及其促进肌腱修复机制，2020-01至2023-12，55万元，在研，主持

2. 上海市科技计划项目，19ZR1432800，BMSCs源exosome通过MFG-E8/αvβ3integrin干预新生鼠梗阻性肾损伤的机制研究，2019-06至2022-05, 20万元，在研，主持

姜大朋

jdp509@163.com

研究成果

近年发表的部分文章：

1. Shi Z, Wang Q, Jiang D; The preventative effect of bone marrow-derived mesenchymal stem cell exosomes on urethral stricture in rats. Transl Androl Urol. 2020 Oct;9(5):2071-2081. doi: 10.21037/tau-20-833.

2. Shi Z, Wang Q, Jiang D; Ascorbic acid mitigates the deleterious effects of nicotine on tendon stem cells. Connect Tissue Res. 2021 Mar;62(2):183-193. doi: 10.1080/03008207.2019.1663349.

3. Wang Q, Shi Z, Jiang D; "Watch and Wait" Strategy for Multicystic Dysplastic Kidney (MCDK): Status Survey of Perceptions, Attitudes, and Treatment Selection in Chinese Pediatric Urologists and Pediatric Surgeons. Front Pediatr. 2020 Jul 28;8:423. doi: 10.3389/fped.2020.00423. eCollection 2020.

4. Shi Z, Wang Q, Zhang Y, Jiang D; Extracellular vesicles produced by bone marrow mesenchymal stem cells attenuate renal fibrosis, in part by inhibiting the RhoA/ROCK pathway, in a UUO rat model. Stem Cell Res Ther. 2020 Jun 26;11(1):253. doi: 10.1186/s13287-020-01767-8.

5. Jiang D, Wang Q, Shi Z, Sun J; Congenital Anomalies of the Kidney and Urinary Tract in Children with Congenital Heart Defects. Kidney Blood Press Res. 2020;45(2):307-313. doi: 10.1159/000504224.

6. Shi Z, Zhang Y, Wang Q, Jiang D; MFG-E8 regulates inflammation and apoptosis in tendon healing, and promotes tendon repair: A histological and biochemical evaluation. IUBMB Life. 2019 Dec;71(12):1986-1993. doi: 10.1002/iub.2143.

7. Shi Z, Wang Q, Jiang D; Extracellular vesicles from bone marrow-derived multipotent mesenchymal stromal cells regulate inflammation and enhance tendon healing. J Transl Med. 2019 Jun 25;17(1):211. doi: 10.1186/s12967-019-1960-x.

8. Wang Q, Shi Z, Jiang D; Matrix Remodeling-Associated Protein 5 in Urinary Exosomes as a Potential Novel Marker of Obstructive Nephropathy in Children With Ureteropelvic Junction Obstruction. Front Pediatr. 2020 Aug 25;8:504. doi: 10.3389/fped.2020.00504.

9. Jiang D, Xu B, Gao P; Effects of young extracellular matrix on the biological characteristics of aged tendon stem cells. Adv Clin Exp Med. 2018 Dec;27(12):1625-1630. doi: 10.17219/acem/75503.

10. Jiang D, Lin H, Chen Z, Xu M, Geng H; Predictive Factors of Contralateral Operation after Initial Pyeloplasty in Children with Antenatally Detected Bilateral Hydronephrosis Due to Ureteropelvic Junction Obstruction. Urol Int. 2018;100(3):322-326. doi: 10.1159/000487196.

11. Jiang D, Gao P, Zhang Y, Yang S; Combined effects of engineered tendon matrix and GDF-6 on bone marrow mesenchymal stem cell-based tendon regeneration. Biotechnol Lett. 2016 May;38(5):885-92. doi: 10.1007/s10529-016-2037-z.

12. Jiang D, Tang B, Xu M, Lin H, Jin L, He L, Xu G, Fang X, Geng H; Functional and Morphological Outcomes of Pyeloplasty at Different Ages in Prenatally Diagnosed Society of Fetal Urology Grades 3-4 Ureteropelvic Junction Obstruction: Is It Safe to Wait? Urology. 2017 Mar;101:45-49. doi: 10.1016/j.urology.2016.10.004.

13. Jiang D, Geng H; Primary Hyperoxaluria. N Engl J Med. 2017 Apr 13;376(15):e33. doi: 10.1056/NEJMicm1609986.